Non-predictors of appropriate therapy
Whilst there were many positive predictive variables associated with
appropriate therapy in the above works, Azoulay et al. also identified
other factors that were not associated with receiving appropriate
therapy in their meta-analysis. These were LBBB, RBBB, a positive
cardiovascular magnetic resonance (CMR) and syncope. Two of the studies
included from this meta-analysis had separately analysed factors that
were non-predictors of appropriate therapy. The conclusions of these
agreed with those from the above meta-analysis, with the exception of
having a lower mean LVEF. This was discussed in Taha et al.’s review(6):
“One found that extent of cardiac involvement on CT-PET and
pre-procedure ventricular arrhythmia (VA) burden were
non-predictors(15). The other described being >60 years
old, New York Heart Association (NYHA) class III/IV, LVEF
<35%, non-sustained VT, paroxysmal atrial fibrillation (AF),
QRS interval >150ms, QTc interval >470ms and
concurrent amiodarone therapy as non-predictors of appropriate
therapy(16)”.