AUTHOR CONTRIBUTIONS
CR, FG, VA, MF, RF participated in data collection; MF, RF prepared libraries; CR, MF, RF, GG, FB performed data analysis and interpreted the results; CR, FG wrote the manuscript with input and critical revision from all co-authors; FG, VA, FG, MR, FL, AB carried out clinical work; ED, CT, PGP, critically revised the study; MA, ET conceived and supervised the study.