Table 2: Secondary Efficacy Outcomes
Outcomes
Effect measure (RR or MD)
95% CI
P value
I2
Change in LVEF
 
 
MD: 4.35
3.11, 5.58
< 0.00001
17%
Change in 6MWT
MD: 15.88
2.86, 28.91
0.02
85%
Change in VO2 max
MD: 3.02
1.81, 4.20
< 0.00001
0%
Change in MLFHQ
MD: -6.73
-11.45, -2.01
0.005
85%
Change in BNP
 
 
MD: -3.48
-24.50, 17.53
0.75
88%
RR- Relative risk, MD- Mean difference, I2- Heterogeneity, LVEF: Left ventricular ejection fraction, MLHFQ: Minnesota living with heart failure questionnaire, 6MWT: Six-minute walk test,
VO2 max: Maximum rate of oxygen consumption, Brain natriuretic peptide.