Title: Remarkable improvement of symptoms and signs of severe dry eye treated by ocular immersion hydrotherapy Yong Tao*, M.D., Haoran Cui, M.D., Shuang Zhang, M.D., Tao Zhang, M.D.Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, P. R. ChinaCorresponding author: Prof. Yong Tao, Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University; No. 8, South Road of Worker’s Stadium, Chaoyang District, Beijing 100020, China. Phone: +86-10-85231405. Fax: +86-10-85231405. E-mail: [email protected] Words: Dry eye disease; Ocular immersion hydrotherapy; Ocular graft-versus-host disease; Corneal epithelial cell damage; Ocular surface inflammation