Introduction 
Hemophilia is an X-linked recessive hemorrhagic disease due to mutations in the F8  gene (hemophilia A or classic hemophilia) or F9  gene (hemophilia B), leading to deficiency of factor VIII and IX respectively. The large size of the F8 gene makes it more susceptible to mutation events than the smaller F9  gene. Thus, Hemophilia A is more common than hemophilia B. Hemophilia affects more than 1.2 million individuals worldwide and occurs in all racial and ethnic groups. The majority of hemophilia patients give a positive family history with an x-linked inheritance pattern. However, a negative family history does not rule out hemophilia, because 20% to 30% of cases arise from a recent mutation, particularly in those with severe disease.1,2
The symptoms and signs of hemophilia A and B are indistinguishable. The severity and onset of bleeding depend on the severity of the disease. The Severity of the disease classified based on the factor activity as severe (<1%), moderate (between 1 and 5%), and mild (between 6 to 40%). Spontaneous bleeding is common in severe disease during early life and in moderate disease, bleeding usually occurs after minor traumas and surgical procedures. 3,4
The presence of hemophilia A and B in one patient is extremely rare, and only a few case reports have been published. The clinical presentation of patients with coexisting hemophilia A and B was similar to the isolated hemophilia. Here, we present a 16-years-old male Ethiopian patient who initially presented with prolonged bleeding of 10 days duration after a circumcision procedure. To the best of our knowledge, this is the only case report from Africa.
Keywords : hemophilia A, hemophilia B