3.2. Effects of high-altitude hypoxia on the metabolism of endogenous substances
CYP are involved in the biosynthesis and catabolism of steroid hormones, vitamins, eicosanoids, fatty acids, and catecholamines. CYP-mediated endogenous metabolites are regulated by hypoxia. CYP-mediated endogenous metabolites are highly correlated with various high-altitude diseases (Figure 2).