3.2. Effects of high-altitude hypoxia on the metabolism of
endogenous substances
CYP are involved in the biosynthesis and catabolism of steroid hormones,
vitamins, eicosanoids, fatty acids, and catecholamines. CYP-mediated
endogenous metabolites are regulated by hypoxia. CYP-mediated endogenous
metabolites are highly correlated with various high-altitude diseases
(Figure 2).