Figure 2. Echocardiograms of the family. A) Echocardiogram of the proband (III.1) with Barlow’s disease showing bi-leaflet prolapse (>2 mm), annular dilatation (51 mm) and mitral annular disjunction (11 mm) and B) echocardiogram of the sister (III.2) with bi-leaflet billowing, annular dilatation (39 mm) and mitral annular disjunction (7 mm). C) Colour echocardiogram of the proband showing severe mitral regurgitation and D) colour echocardiogram of the sister showing mild mitral regurgitation.