Conclusion
Types of ICS devices are associated with different saliva microbiome
composition in moderate-to-severe pediatric asthma. The causal relation
between inhaler types and changes in saliva microbiota composition needs
to be further evaluated, as well as whether this leads to different
potential adverse effects in terms of occurrence and level of severity.
Keywords: Asthma, Inhaled Corticosteroids, Metered Dose
Inhaler, Dry Powder Inhaler, Microbiome, Saliva