Introduction
Systemic amyloid A (AA) amyloidosis  is usually secondary to various chronic infectious , while amyloid light-chain (AL)amyloidosis is associated with plasma cell dyscrasia. In the literature, only few studies report correlations between infections and AL amyloidosis. We report an unusual case of AL amyloidosis developing in the setting of chronic hepatitis B and HIV infections.
Our clinical case suggests a link between chronic infections and eventual onset of AL amyloidosis. There is suspicion that AL amyloidosis is linked to systemic inflammation of the body, but more research is needed to confirm this. Furthermore, the case was a great therapeutic challenge , based on the balance between antiviral and immunosuppressive therapy.