1-Introduction
The Ewing sarcoma family of tumours (ESFT) represents a group of classic
Ewing’s sarcoma of bone, extra skeletal Ewing’s sarcoma (EES), Askin
tumours of the chest wall and primitive neuroectodermal tumours of bone
or soft tissues1. The translocation t(11; 22) (q24;
q12), which produces the EWS/FLI1 fusion gene is the genetic bases of
ESFT2. The tumor cells are an undifferentiated small
round blue cell with a low mitotic index3.
Ewing sarcoma (ES) of the bone is the second most frequent malignant
bone cancer in adolescents and young adults after
osteosarcoma4. EES is an uncommon condition that can
appear anywhere in the soft tissues and can alter the cortex of nearby
bone. The trunk, extremities, and retroperitoneum are the areas where it
occurs most frequently5.
However, the existence of metastatic disease is the most crucial
prognostic marker, and even patients who are diagnosed with locally
limited cancer are at significant risk of developing metastatic disease
while receiving local therapy6.
While Ewing sarcoma is primarily a bone cancer, it rarely metastasizes
to the pancreas7. In this case report, we present a
38-year-old man with cytogenetically confirmed metastatic ES to the
pancreas.