1-Introduction
The Ewing sarcoma family of tumours (ESFT) represents a group of classic Ewing’s sarcoma of bone, extra skeletal Ewing’s sarcoma (EES), Askin tumours of the chest wall and primitive neuroectodermal tumours of bone or soft tissues1. The translocation t(11; 22) (q24; q12), which produces the EWS/FLI1 fusion gene is the genetic bases of ESFT2. The tumor cells are an undifferentiated small round blue cell with a low mitotic index3.
Ewing sarcoma (ES) of the bone is the second most frequent malignant bone cancer in adolescents and young adults after osteosarcoma4. EES is an uncommon condition that can appear anywhere in the soft tissues and can alter the cortex of nearby bone. The trunk, extremities, and retroperitoneum are the areas where it occurs most frequently5.
However, the existence of metastatic disease is the most crucial prognostic marker, and even patients who are diagnosed with locally limited cancer are at significant risk of developing metastatic disease while receiving local therapy6.
While Ewing sarcoma is primarily a bone cancer, it rarely metastasizes to the pancreas7. In this case report, we present a 38-year-old man with cytogenetically confirmed metastatic ES to the pancreas.