References:
1. Wagner G, Fenchel K, Back W, Schulz A, Sachse MM. Leukemia cutis - epidemiology, clinical presentation, and differential diagnoses. J Dtsch Dermatol Ges J Ger Soc Dermatol JDDG . 2012;10(1):27-36. doi:10.1111/j.1610-0387.2011.07842.x2. Robak E, Braun M, Robak T. Leukemia Cutis-The Current View on Pathogenesis, Diagnosis, and Treatment. Cancers . 2023;15(22):5393. doi:10.3390/cancers152253933. Du AX, Hung T, Surmanowicz P, Gniadecki R. Diagnostic challenge of aleukemic leukemia cutis preceding acute myelogenous leukemia: A case report. SAGE Open Med Case Rep . 2020;8:2050313X20919638. doi:10.1177/2050313X209196384. Su WP, Buechner SA, Li CY. Clinicopathologic correlations in leukemia cutis. J Am Acad Dermatol . 1984;11(1):121-128. doi:10.1016/s0190-9622(84)70145-9Figure legends:
Figure 1: a) giant nodular red lesion measuring almost 16 cm, with overlying ulceration and crusting on the patient left shoulder. b) peripheral blood smear showing blast cell.
Figure 2: a) HE stain x100 showing atypical large lymphoid cells in a perivascular pattern in the dermis without epidermal involvement. b) immunohistochemistry positive for tdt and CD2 makers. c) rapid amelioration and involution of the lesion after the first cycle of chemotherapy.
Acknowledgments: none.