3.3 MUC18 Expression in Each Cell Model
The MUC18 protein was positively expressed in the melanoma cell lines
A375, HMVII and SK-Mel-28 but was not expressed in the A549 cell line
(Figure 2F). The results showed that the expression of MUC18 was highest
in SK-Mel-28 cells (1.04 ± 0.04), similar in A375 cells and HMVII cells
(0.83 ± 0.01, 0.83 ± 0.02), and lowest in A549 cells (0.01 ± 0.001)
(Figure 2G). These findings suggested that the three melanoma cell lines
can be used as positive models and that the A549 cell line can be used
as a negative model.