Conclusion
This study revealed that HCQ was associated with increased platelet counts in children with chronic ITP. We did not find interaction effect of ANA level on the treatment efficacy of HCQ. Meanwhile, some side effects were also observed, indicating that weighting the advantages and disadvantages when planning to introduce it are of importance. Before using HCQ as a proposed therapy for children with ITP, it is necessary to identify its appropriate population and explore drug monitoring methods.