Compared to the six representative reference strains, the Korean strains carry four specific mutations in LT-ag: a T> C substitution at position 1,501 in JL93; a T> C substitution at position 1,466; a G> A substitution at position 1,489; and a T> C substitution at position 1,572 in JL95 (Figure 2 and Supplementary Figure S1). In addition, the Korean strains showed two specific mutations in the VP1 gene: a T > G substitution at position 4,152 and a G > A substitution at position 4,153 in three samples (BL1, BL4, and BL28). At positions 4,362 and 4,368, two point mutations were found to be present in a mixed form: G > A (North American/European/TKS strains) and A > G (China/Korean strains) (Figure 3 and Supplementary Figure S2).