FIGURE 3 . Averaged skin LC-OCT intensity profilesR (z ) as a function of depth of one volunteer before (black dashed line) and after (black solid line) OC with mixture of Polyethylene glycol, Oleic acid and Propylene glycol with linear regression fit lines of epidermal and dermal layers and correspondingµ s estimated values. Round insets display LC-OCT horizontal sections of dermal layer at 200 µm depth before (t = 0 min) and after OC (t = 11 min). The graphs next to the insets are the corresponding pixel intensity distributions.
Relative changes (in % of intact skin value) of scattering coefficients\(µ_{s}^{\text{epi}}\) and \(µ_{s}^{\text{der}}\) (of epidermal and dermal layers, respectively) for the nine OCA and a control condition as a function of time are presented in Figure 4 . Similar results, but for epidermal/dermal scattering anisotropy factorg epidermis and g dermisare presented in Figure 5 . SD bars that represent the variation between three volunteers vere removed from the graphs for the sake of clarity (due to strong overlapping between bars) and presented separately in Table 2 (mean values over 10 timepoints) with respect to optical property, layer and OCA used.