Results and Conclusion:
Biopsies confirmed a coinfection of CMV and HSV-1. Treatment commenced
with valganciclovir and a temporary halt to mycophenolate, resulting in
undetectable CMV levels subsequently. A follow-up EGD conducted two
months later showed that the esophageal ulcers had no new bleeding, and
biopsies indicated candida esophagitis without signs of CMV or HSV
infection. The diagnosis of CMV and HSV-1 coinfection is a rare
occurrence but crucial to identify due to its association with higher
complication rates, including perforation and bleeding (1).