Key clinical message
Serum sickness is rare; however, there is a significant hypersensitivity
reaction to streptokinase used in different cardiac problems. Treatment
often involves discontinuing the offending agent and administering
corticosteroids, which can lead to complete recovery. This case
underscores the complexities of managing prosthetic valve thrombosis and
highlights the importance of monitoring and addressing potential
complications of thrombolytic therapy.