Case
A 6-month-old male infant presented with a primary complaint of seizures
persisting for one week. A non-contrast CT scan of the head revealed
several significant findings. There was a marked thinning of the corpus
callosum accompanied by colpocephaly, characterized by disproportionate
dilation of the occipital horns of the lateral ventricles. Along the
bilateral lateral ventricular walls, nodular tissue with attenuation
patterns consistent with grey matter was observed, suggestive of
subependymal grey matter heterotopia. Additionally, features suspicious
for closed-lip bilateral parieto-occipital schizencephaly were
identified. Further CT scan dilated cerebrospinal fluid spaces within
the left posterior fossa and benign enlargement of the subarachnoid
spaces. (Figure 1, 2, 3, 4, 5) However, the calvarium, cerebral
hemispheres, basal ganglia, and brainstem were structurally normal, with
no evidence of midline shift or mass effect. These imaging findings
collectively suggest a diagnosis of subependymal grey matter heterotopia
associated with corpus callosum dysgenesis, colpocephaly, and potential
schizencephaly. The dilated posterior fossa and subarachnoid spaces
appear to be incidental findings, likely of benign origin.