Rotavirus A (RVA) is a major cause of viral acute gastroenteritis (AGE) in infants and young children worldwide1-4. RVA-associated AGE is a global concern, affecting 128,500 children under 5 years of age globally in 20165. Notably, within Southeast Asia, RVA-associated diarrhea accounted for 40.8% of cases between 2008 and 2018, and is the leading cause of illness and mortality among children under 5 years of age6. In Indonesia in 2016-2018, the prevalence of RVA infection in patients under five years of age was 31.7%-55.4%, and RVA was a major cause of acute gastroenteritis in hospitalized patients in pediatric hospitals and general hospitals7.