Fig. 7 Long-term magnetothermal neurostimulation mediated by FVIOs. (a) Percentage of freezing time in mice on the 60th day after injection of anti-His-FVIOs (or anti-His-SPIOs) before and after magnetothermal treatment. The data are presented as the means ± SEM. (b) UTE MR images of mouse brains used to evaluate the amount of anti-His-FVIOs (or anti-His-SPIOs) remaining in the CeA regions on the 1st, 30th, and 60th days. (c) Plots of the relative T2 signal intensity to noise in the CeA regions in the UTE MR images obtained from FVIO- and SPIO-treated mice.