1.Introduction:
Globally, the most common cause of viral hepatitis and a significant
factor in end-stage liver disease is the hepatitis B virus (HBV)
[1]. Approximately thirty million people are newly infected with HBV
each year globally, and a total of 296 million people are currently
living with chronic HBV [2]. Autoantibodies, usually of the IgG
subtype, known as antineutrophil cytoplasmic antibodies (ANCAs), are
directed against lysosomal components and azurophilic granules found in
the cytoplasm of neutrophils and monocytes. The incidence of ANCAs in
the general population is thought to be minimal (less than 5%), making
them sensitive and specific indicators of ANCA-associated vasculitis
[3]. Here, We provide a case of a male patient in his middle age who
was diagnosed with c-ANCA-associated small vessel vasculitis secondary
to Hepatitis B. Our case involves a rare occurrence of chronic hepatitis
associated with c-ANCA-associated vasculitis. It helps us better
understand this rare occurrence and enables us to manage it timely.