4.CONCLUSION:
In conclusion, the case presents the unusual relationship between HBV infection and autoimmune-mediated C-ANCA-associated small vessels as an initial presentation of chronic HBV infection. This rare association highlights the importance of considering vasculitis in the differential diagnosis of patients with HBV, even in the absence of liver-related symptoms. The presence of cANCA in such cases prompts further investigation into the immunological mechanisms underlying HBV-associated vasculitis, suggesting a potential role for ANCA testing in CHB patients presenting with vasculitis symptoms. Continued research is essential for better understanding this complex association’s mechanisms and management strategies.