Statistical analysis
Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) software (version 25; Armonk, NY: IBM Corp.). The Kolmogorov–Smirnov and Shapiro–Wilk tests were conducted to determine the normal distribution of data. Student’s t-test was conducted to compare the continuous parametric variables. The Mann–Whitney U-test was conducted to compare variables with non-normal distribution. Chi-squared or Fisher’s exact test was conducted to analyze the categorical variables. Categorical variables were expressed as numbers (%). Normally distributed variables were expressed as mean ± standard deviation values. Non-parametric continuous variables were expressed as median values (interquartile range). The difference with p < 0.05 was considered statistically significant.