Study Population
All children admitted to the intensive care unit (ICU) at St. Jude Children’s Research Hospital, a specialized pediatric hematologic-oncology hospital, who received CKRT from January 2010 to August 2022 were screened. Patients were included if they underwent HCT and had SOS at the time of the CKRT course. The study was approved by the St. Jude Children’s Research Hospital Institutional Review Board. The PrismaFlex CKRT system (Gambro/Baxter) was used for all patients. All patients received continuous regional citrate infusion for anticoagulation and continuous systemic calcium infusion.