Study Population
All children admitted to the intensive care unit (ICU) at St. Jude
Children’s Research Hospital, a specialized pediatric
hematologic-oncology hospital, who received CKRT from January 2010 to
August 2022 were screened. Patients were included if they underwent HCT
and had SOS at the time of the CKRT course. The study was approved by
the St. Jude Children’s Research Hospital Institutional Review Board.
The PrismaFlex CKRT system (Gambro/Baxter) was used for all patients.
All patients received continuous regional citrate infusion for
anticoagulation and continuous systemic calcium infusion.