Key Clinical Message
Methadone-induced strabismus is a rare but potentially serious
complication of opioid toxicity. Healthcare providers should be vigilant
for uncommon neurological and ocular manifestations in patients
presenting with methadone overdose, particularly in opioid-naive
individuals. Prompt recognition and appropriate management, including
the administration of naloxone and supportive care, are essential to
prevent long-term morbidity and mortality associated with methadone
toxicity.