2.4 | Statistical Analysis
This study was a retrospective comparison of two main groups of patients: those who tested positive or negative for an RVI pre-admission and/or upon admission. Patients who tested positive were further categorized as having a high- or low-risk infection and as to whether the patient presented with LR and/or UR symptoms.
We reported demographic and other characteristics as well as outcomes overall and by RVI group: RVI negative; RVI positive, low-risk, asymptomatic; RVI positive, low-risk, symptomatic; RVI positive, high-risk, asymptomatic; and RVI positive, high-risk, symptomatic. We also presented results collapsing all RVI positive groups to a single group. Summary statistics include the frequency of each categorical characteristic and five number summaries (mean, standard deviation, median, interquartile range, minimum, and maximum) for each continuous or ordinal characteristic.
We used contingency tables and logistic regression models to evaluate differences in the primary outcomes among the RVI groups. Categorical data were presented with their counts and frequencies and depending on cell counts were statistically tested using either the Chi-Square Test or the Fisher’s Exact Test. We used similar methods to evaluate all secondary outcomes. The overall model was first evaluated, with the overall model p-value adjusted for multiple tests using the Holm procedure. Further comparison of RVI groups was only conducted if the overall model test was significant.
3 | Results :
Table 1-4 present detailed data for all patients. Figures 1-3 present findings based on data and statistical analyses.