RESULTS
A total of 319,480 cancer and AF-related deaths occurred among adults
between 1999 and 2019. The overall AAMR was 4.95 (95% CI: 4.84 to 5.05)
in 1999, increasing to 10.01 (9.88 to 10.13) in 2019, with an AAPC of
3.49 (3.39 to 3.60). The AAMR rose from 1999 to 2015 (APC: 3.03, 2.87 to
3.17) and surged until 2019 (APC: 5.36, 4.63 to 6.62) (Figure
1A ). Males consistently exhibited higher AAMRs compared to females
(10.24 [10.19 to 10.29] vs 5.13 [5.10 to 5.16]). However, both
genders experienced a similar increase in AAMRs (males: AAPC: 3.30;
[3.20 to 3.42]; females: AAPC: 3.36; [3.18 to 3.50];Figure 1A ). Among racial groups, the NH White population
demonstrated the highest AAMR (7.56 [7.53 to 7.59]), followed by NH
Black (4.44 [4.38 to 4.51]) and Hispanic (3.11 [3.04 to 3.17]).
Hispanics showed the greatest AAMR increase (AAPC: 4.55; [4.03 to
5.30]), followed by NH Whites (AAPC: 3.66; [3.49 to 3.82]) and NH
Blacks (AAPC: 3.33; [3.01 to 3.73]) (Figure 1B ). States in
the top 90th percentile for AAMR were Vermont, Minnesota, Rhode Island,
Nebraska, and Oregon, while states in the bottom 10th percentile
included Arizona, Georgia, New Mexico, Louisiana, and Nevada
(Figure 1C ).