Collection of lens capsule
This study received ethical approval from the Medical Science Research
Ethics Committee of Shanghai Ninth People’s Hospital (Approval No.
SH9H-2023-T64-2). A total of sixteen patients diagnosed with cataracts
were recruited from the Department of Ophthalmology, Shanghai Ninth
People’s Hospital. Of these, nine patients were diagnosed with
age-related cataracts and served as the control group, while seven
patients with high myopic cataracts comprised the experimental group.
All participants, or their legal guardians, were thoroughly informed
about the study and provided written informed consent. Patients’
information was shown in Tables S1 in supplementary information (SI).
The lens capsules were collected in the standard step of capsulorhexis
during cataract surgery and preserved in a tissue storage solution for
future use.