HIIT reversed the OA-induced inflammatory response
Compared with control rats, the contents of SP and IL-6 in the serum of
OA rats were significantly increased. However, HIIT can reduce the
contents of SP and IL-6 in the serum of OA rats (P <
0.05, Figure 3A ). IHC analyzed the inflammatory factors of the
cartilage extracellular matrix. Compared with control rats, the
expression of MMP-13 and IL-6 displayed significantly increased in OA
rats. However, HIIT decreased MMP-13 and IL-6 expression of OA rats
(P < 0.05, Figure 3 B-C).