AUC, Cmax, and elimination half-life of tezacaftor-ivacaftor real-world compared to reported values
AUC0-24h for tezacaftor(-M1) and AUC0-12h for ivacaftor(-M1 and –M6), Cmax, and terminal elimination half-life (t1/2,β) were assessed during every occasion by Bayesian analysis. The obtained values were compared to their reported values as described in the product information. (3)