Recurrent preschool wheeze- What do we know?
Many have clinical symptom resolution by school age and do not develop allergic asthma. Transient wheezers are usually non atopic, resolves during the preschool years suggesting non-allergic drivers. Corticosteroids are thus not as beneficial compared to allergic asthma. The pathogens associated with acute episodes of wheezing in preschool children may be distinct from those in school-age asthma. Acute wheeze episodes associated with hypopharyngeal bacterial infection; 85% of the time Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis; as well as nasopharyngeal viral infection.1