I'm S. Jay Olshansky, an epidemiologist at the University of Illinois at
Chicago School of Public Health. I study human longevity and am part of
a study group investigating whether a drug used to treat diabetes can
slow the aging process. Ask me anything!
Abstract
Hi Reddit! I am S. Jay Olshansky and I’m a professor of epidemiology in
the University of Illinois at Chicago School of Public Health. I’m also
on the board of directors of the American Federation of Aging Research;
the first author of The Quest for Immortality: Science at the Frontiers
of Aging (Norton, 2001); A Measured Breath of Life(2013); and co-editor
of Aging: The Longevity Dividend(Cold Spring Harbor Laboratory Press,
2015). I have spearheaded The Longevity Dividend Initiative – an effort
to extend the period of healthy life by slowing aging. I study the upper
limits of longevity and ask which populations are living longer and why,
and what that means for society. Living a longer life is a monumental
achievement of public health and modern medicine – it is exactly what
we set out to achieve more than a hundred years ago when life was short.
More people today are living to 65, 85, and 100 and beyond than ever
before, but it has created a Faustian trade. In exchange for our longer
lives, we now live long enough to experience heart disease, cancer,
sensory impairments, and Alzheimer’s disease. The fact is that our
bodies were not “designed” for long-term use . While improved
lifestyles can enhance health and quality of life, the aging process
marches on unaltered beneath the surface – leading to the diseases and
disorders we fear most. My research focuses on investigating ways to
extend the period of healthy life and compress sickness and disease as
much as possible to the very end. Recently I have teamed with a group of
researchers to study the ability of the diabetes drug metformin to do
just that; although metformin is just one of many research pathways
scientists are pursuing to slow biological aging. My research suggests
that slowing down aging will be the next great public health advance in
this century because it targets multiple age-related chronic diseases.
Importantly, this approach to public health can save far more health
care dollars than treating one disease at a time. The time has arrived
to take a new approach to chronic fatal and disabling diseases. I’ll be
back at 1 pm EST (10 am PST, 6 pm UTC) to answer your questions, ask me
anything!