Efficacy of eculizumab in refractory life-threatening warm autoimmune
hemolytic anemia associated with chronic myelomonocytic leukemia.
Abstract
We report a case of refractory life-threatening warm autoimmune
hemolytic anemia (wAIHA) associated with chronic myelomonocytic leukemia
(CMML) for which all conventional treatments had failed. The use of
eculizumab allowed controlling hemolysis and resulted in transfusion
independence. These data support the use of eculizumab in refractory
wAIHA.