Patient management positive covid: the central role of clinical
nutrition and supplementation of essential amino acids during and after
hospitalization..
Abstract
Background The covid 19 positive patient who is subject to a
hyperinflammatory condition associated with lung injury with the
development of pneumonia is hospitalized in the intensive care unit.
Before resolving and overcoming the “cytokine storm”, with
overexpression of pro-inflammatory interleukins (IL-, Il-6), this
patient will be intubated for more than 48 hours and therefore needs
adequate nutrition. Experimental approach Malnutrition can lead to
sarcopenia with a decrease in lean body mass and worsening of the
inflammatory state underway. In addition, severe debilitation, if not
corrected with adequate nutrition, can greatly lengthen rehabilitation
times with prolonged hospitalization, increased costs and reduced turn
over already in crisis due to the health emergency caused by
coronavirus. Key Results The aim of this study is to focus attention on
the nutritional importance that must be provided in case of covid 19
together with pharmacological treatments to lower the number of
circulating proinflammatory cytokines. Conclusions Oral, enteral and
parenteral nutrition should always be carried out according to the
patient’s condition and, in the case of a hyperinflammatory patient,
such as the one affected by covid 19, it has been shown that the
supplementation of amino acids helps to lower the inflammatory state and
promotes normal recovery physiological. Keywords: amino acids,
nutrition, covid, glutamine, hyperinflammatory, sarcopenia, cytokine.