Hepatitis B virus core-related antigen is useful for surveillance of hepatocellular carcinoma recurrence in a patient with occult hepatitis B virus infection: Case report

Keiji Yokoyama; Eri Yamauchi; Yotaro Uchida; Takanori Kitaguchi; Hiromi Fukuda; Ryo Yamauchi; Naoaki Tsuchiya; Kaoru Umeda; Kazuhide Takata; Takashi Tanaka; Shinjiro Inomata; Daisuke Morihara; Yasuaki Takeyama; Satoshi Shakado; Shotaro Sakisaka; Fumihito Hirai

doi:10.22541/au.159225371.10290044

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Hepatitis B virus core-related antigen is useful for surveillance of hepatocellular carcinoma recurrence in a patient with occult hepatitis B virus infection: Case report

Keiji Yokoyama,
Eri Yamauchi,
Yotaro Uchida,
Takanori Kitaguchi,
Hiromi Fukuda,
Ryo Yamauchi,
Naoaki Tsuchiya,
Kaoru Umeda,
Kazuhide Takata,
Takashi Tanaka,
Shinjiro Inomata,
Daisuke Morihara,
Yasuaki Takeyama,
Satoshi Shakado,
Shotaro Sakisaka,
Fumihito Hirai

Abstract

A 73-year-old woman with occult hepatitis B virus (HBV) infection was diagnosed with hepatocellular carcinoma (HCC). Serum HBV core-related antigen (HBcrAg) was elevated and HBV covalently closed circular DNA (cccDNA) was presented in the liver tissue. This report shows HBcrAg might be a predictive factor for development of HCC.

12 Jun 2020Submitted to Clinical Case Reports

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14 Jun 2020Submission Checks Completed

14 Jun 2020Assigned to Editor

24 Jun 2020Reviewer(s) Assigned

18 Jul 2020Review(s) Completed, Editorial Evaluation Pending

27 Jul 2020Editorial Decision: Revise Minor

10 Aug 20201st Revision Received

11 Aug 2020Submission Checks Completed

11 Aug 2020Assigned to Editor

11 Aug 2020Review(s) Completed, Editorial Evaluation Pending

19 Aug 2020Editorial Decision: Revise Minor

24 Aug 20202nd Revision Received

24 Aug 2020Submission Checks Completed

24 Aug 2020Assigned to Editor

24 Aug 2020Review(s) Completed, Editorial Evaluation Pending

25 Aug 2020Editorial Decision: Accept

Abstract

Peer review status:ACCEPTED