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Lymphomatoid granulomatosis of the central nervous system (CNS-LYG), immune thrombocytopenia, disseminated zoster and venous thrombosis: “Hickam’s dictum posing a management challenge”
  • +6
  • Mohsin Soleja,
  • Jesse Jaso,
  • Weina Chen,
  • Jack Raisanen,
  • Christian Wysocki,
  • Yu-Min Shen,
  • Bruce Mickey,
  • Kiran Kumar,
  • Praveen Ramakrishnan Geethakumari
Mohsin Soleja
UT Southwestern

Corresponding Author:[email protected]

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Jesse Jaso
The University of Texas Southwestern Medical Center
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Weina Chen
UT Southwestern Medical School
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Jack Raisanen
The University of Texas Southwestern Medical Center
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Christian Wysocki
UT Southwestern Medical Center
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Yu-Min Shen
University of Texas Southwestern Medical Center
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Bruce Mickey
The University of Texas Southwestern Medical Center
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Kiran Kumar
The University of Texas Southwestern Medical Center
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Praveen Ramakrishnan Geethakumari
University of Texas Southwestern Medical Center at Dallas
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Abstract

We describe a case of isolated primary CNS lymphomatoid granulomatosis and a discordant low-grade B-cell lymphoma involving the bone marrow causing chronic immune thrombocytopenia. Clinical course was complicated with disseminated zoster and sub-massive pulmonary embolism. Our patient was successfully managed with a combination radioimmunotherapy strategy with rituximab and radiation therapy.
09 Jan 2021Submitted to Clinical Case Reports
11 Jan 2021Submission Checks Completed
11 Jan 2021Assigned to Editor
20 Jan 2021Reviewer(s) Assigned
29 Jun 2021Review(s) Completed, Editorial Evaluation Pending
06 Jul 2021Editorial Decision: Revise Minor
09 Jul 20211st Revision Received
09 Jul 2021Submission Checks Completed
09 Jul 2021Assigned to Editor
09 Jul 2021Review(s) Completed, Editorial Evaluation Pending
12 Jul 2021Reviewer(s) Assigned
22 Aug 2021Editorial Decision: Accept