Chemoradiation for Pediatric Primary Cardiac Leiomyosarcoma: Case Report
and Review of Literature
- James Janopaul-Naylor,
- Kirk Kanter,
- Thomas Olson,
- Bree Eaton
Abstract
A 13-year-old healthy girl presented with dizziness and palpitations,
found to have a left atrial mass. An 8 cm tumor was removed. Pathology
confirmed leiomyosarcoma, Grade 3 with positive margins. She was treated
with ifosfamide and doxorubicin prior to radiation with concurrent
ifosfamide alone. She was treated to 66 Gy in 33 fractions to the
operative bed. Prospectively graded toxicities included Gr 2 esophagitis
and Gr 1 anorexia, dermatitis and fatigue. She completed a total of 6
cycles of ifosfamide. One year after treatment she had no evidence of
disease with normal ECHO and no cardiac, pulmonary or esophageal
symptoms.19 Apr 2021Submitted to Pediatric Blood & Cancer 19 Apr 2021Submission Checks Completed
19 Apr 2021Assigned to Editor
23 Apr 2021Reviewer(s) Assigned
25 May 2021Review(s) Completed, Editorial Evaluation Pending
25 May 2021Editorial Decision: Revise Minor
28 Jun 20211st Revision Received
28 Jun 2021Submission Checks Completed
28 Jun 2021Assigned to Editor
05 Jul 2021Review(s) Completed, Editorial Evaluation Pending
05 Jul 2021Editorial Decision: Accept