Essential Site Maintenance: Authorea-powered sites will be updated circa 15:00-17:00 Eastern on Tuesday 5 November.
There should be no interruption to normal services, but please contact us at [email protected] in case you face any issues.

loading page

Triple Semicircular Canal Occlusion Combined with Endolymphatic Sac Decompression: An Effective Surgical Strategy for Vertigo Control of Intractable Meniere’s Disease
  • +3
  • Bingbin Xie,
  • Meiqun Wang,
  • Yunxia Jiang,
  • Wen Xie,
  • Shaorong Zhang,
  • Yuehui Liu
Bingbin Xie
The Second Affiliated Hospital of Nanchang University

Corresponding Author:[email protected]

Author Profile
Meiqun Wang
The Second Affiliated Hospital of Nanchang University
Author Profile
Yunxia Jiang
The Second Affiliated Hospital of Nanchang University
Author Profile
Wen Xie
The Second Affiliated Hospital of Nanchang University
Author Profile
Shaorong Zhang
The Second Affiliated Hospital of Nanchang University
Author Profile
Yuehui Liu
The Second Affiliated Hospital of Nanchang University
Author Profile

Abstract

Objective: To investigate the symptomatic relief and functional preservation of a novel surgical strategy combined with triple semicircular canal occlusion and endolymphatic sac decompression in patients with intractable Meniere’s disease. Design: Retrospective analysis. Setting: Patients with intractable Meniere’s disease in the Department of Otolaryngology Head & Neck in the Second Affiliated Hospital of Nanchang University between July 2015 and June 2019. Participants: Data from 46 patients diagnosed with Meniere’s disease, and underwent surgery Methods: Triple semicircular canal occlusion combined with endolymphatic sac decompression was performed in all patients with intractable Meniere’s disease. Pre- and postoperative vertigo attacks, hearing levels, tinnitus, aural fullness, and equilibrium function rehabilitation were analyzed at defined time points during follow-up. Results: A significant vertigo control rate was observed in all patients postoperatively. The overall control rate of vertigo postoperatively was 100% in the entire follow-up, with a complete control rate of 97.8% and a substantial control rate of 2.2%. The rate of hearing preservation was 54.35%, and all patients suffering from hearing deterioration were at stages III and IV. The rate of tinnitus and aural fullness alleviation was 65.8% and 100%, respectively. Four patients failed to regain the equilibrium function postoperatively. Conclusion: Combining triple semicircular canal occlusion with endolymphatic sac decompression is an efficient strategy for vertigo control in patients with intractable Meniere’s disease. Patients in advanced stages suffered more from hearing function deterioration. Hearing preservation and tinnitus alleviation warrant further investigation.
29 Mar 2021Submitted to Clinical Otolaryngology
12 Apr 2021Submission Checks Completed
12 Apr 2021Assigned to Editor
21 Apr 20211st Revision Received
07 May 2021Submission Checks Completed
07 May 2021Assigned to Editor
09 May 2021Reviewer(s) Assigned
03 Jun 2021Review(s) Completed, Editorial Evaluation Pending
04 Jun 2021Editorial Decision: Revise Major
21 Jun 20212nd Revision Received
23 Jun 2021Submission Checks Completed
23 Jun 2021Assigned to Editor
23 Jun 2021Reviewer(s) Assigned
01 Jul 2021Review(s) Completed, Editorial Evaluation Pending
06 Jul 2021Editorial Decision: Revise Minor
10 Jul 20213rd Revision Received
12 Jul 2021Submission Checks Completed
12 Jul 2021Assigned to Editor
13 Jul 2021Reviewer(s) Assigned
06 Aug 2021Review(s) Completed, Editorial Evaluation Pending
08 Aug 2021Editorial Decision: Accept
Mar 2022Published in Clinical Otolaryngology volume 47 issue 2 on pages 319-322. 10.1111/coa.13852