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Invasive multifocal cryptococcal airway disease in a teenager with hypogammaglobulinaemia
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  • Michael-John Fay,
  • Catherine Byrnes,
  • Naveen Pillarisetti,
  • Andrew Fox-Lewis,
  • Brent McSharry,
  • Annaliesse Blincoe,
  • Colin Barber,
  • Jan Sinclair,
  • Emma Best
Michael-John Fay
Starship Children's Hospital Child Protection Service

Corresponding Author:[email protected]

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Catherine Byrnes
University of Auckland
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Naveen Pillarisetti
Starship Children's Health
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Andrew Fox-Lewis
Auckland City Hospital
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Brent McSharry
Starship Children's Health
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Annaliesse Blincoe
Starship Children's Health
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Colin Barber
Starship Children's Health
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Jan Sinclair
Starship Children's Health
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Emma Best
Starship Children's Health
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Abstract

Cryptococcosis is an invasive, opportunistic, fungal infection that predominantly effects the respiratory tract and central nervous system in immunocompromised patients. It is classically associated with defects in cellular immunity such as acquired immunodeficiency syndrome. Here we describe a case of life-threatening laryngitis, endobronchitis and pneumonia due to Cryptococcus neoformans in a teenager with hypogammaglobulinaemia. To the best of our knowledge, no previous cases of laryngeal cryptococcosis have been reported in the paediatric population.
04 Aug 2021Submitted to Pediatric Pulmonology
04 Aug 2021Submission Checks Completed
04 Aug 2021Assigned to Editor
08 Aug 2021Reviewer(s) Assigned
16 Aug 2021Review(s) Completed, Editorial Evaluation Pending
16 Aug 2021Editorial Decision: Revise Major
09 Sep 20211st Revision Received
09 Sep 2021Reviewer(s) Assigned
09 Sep 2021Submission Checks Completed
09 Sep 2021Assigned to Editor
15 Sep 2021Review(s) Completed, Editorial Evaluation Pending
21 Sep 2021Editorial Decision: Accept