Essential Site Maintenance: Authorea-powered sites will be updated circa 15:00-17:00 Eastern on Tuesday 5 November.
There should be no interruption to normal services, but please contact us at [email protected] in case you face any issues.

loading page

Heart transplantation at the Peruvian National Heart Institute: One-decade single-center experience
  • +3
  • Miguel Pinto-Salinas,
  • Julio Morón-Castro,
  • Fernando Chavarri-Velarde,
  • Franz Soplopuco-Palacios,
  • Luis Palma-Ortecho,
  • Miguel Lescano-Alva
Miguel Pinto-Salinas
Universidad Nacional Mayor de San Marcos

Corresponding Author:[email protected]

Author Profile
Julio Morón-Castro
Universidad Nacional Mayor de San Marcos
Author Profile
Fernando Chavarri-Velarde
Universidad Nacional Mayor de San Marcos
Author Profile
Franz Soplopuco-Palacios
Department of Cardiovascular Surgery Instituto Nacional Cardiovascular “Carlos Alberto Peschiera Carrillo” Lima Peru
Author Profile
Luis Palma-Ortecho
Department of Cardiopediatrics Instituto Nacional Cardiovascular “Carlos Alberto Peschiera Carrillo” Lima Peru
Author Profile
Miguel Lescano-Alva
Department of Clinical Cardiology Instituto Nacional Cardiovascular “Carlos Alberto Peschiera Carrillo” Lima Peru
Author Profile

Abstract

Background: Heart transplantations are ideal for most patients with end-stage heart failure refractory to medical treatment. The transplantation program at the Peruvian National Heart Institute started with a 10-year-continuity in 2010. Objective: To report the results of a 10-year heart transplantation experience at the Peruvian National Heart Institute. Methods: We studied 83 patients who underwent orthotopic heart transplantation at a single center between January 2010 and December 2019. The recipients’ profiles and survival were analyzed according to sex and age group, ensuring the information’s confidentiality. Results: The recipients’ mean age was 41.2 ± 17 years, 88% were adult, and 68.7% were male. The main indications for transplantation were idiopathic dilated cardiomyopathy. 85.5% of recipients were clinically categorized as INTERMACS Profile 1 to 3 before transplantation. There was a significant difference between sexes regarding the preoperative left ventricular ejection fraction and between age groups regarding the waiting time. The average ischemia time was 3.1 hours, operating time was 6.1 hours, cardiopulmonary bypass time was 3 hours, and aortic cross-clamp time was 1.7 hours. The principal early postoperative complications were hematological disorders and acute kidney failure. The principal late ones were kidney failure and severe anemia. The postoperative mortality was 15.9%, and the principal causes were infection and then acute rejection. The survival at one, five, and ten years was 87.5%, 79.8%, and 79.8%, respectively. The survival results were not influenced by sex or age group. Conclusion: Our patients’ postoperative complications, mortality, and survival rates coincided with those reported by the ISHLT registry.
23 Oct 2021Submitted to Journal of Cardiac Surgery
26 Oct 2021Submission Checks Completed
26 Oct 2021Assigned to Editor
26 Oct 2021Reviewer(s) Assigned
07 Nov 2021Review(s) Completed, Editorial Evaluation Pending
15 Nov 2021Editorial Decision: Revise Major
22 Dec 20211st Revision Received
23 Dec 2021Submission Checks Completed
23 Dec 2021Assigned to Editor
23 Dec 2021Reviewer(s) Assigned
13 Jan 2022Review(s) Completed, Editorial Evaluation Pending
13 Jan 2022Editorial Decision: Accept
Jun 2022Published in Journal of Cardiac Surgery volume 37 issue 6 on pages 1550-1558. 10.1111/jocs.16429