Nano-Bio-Engineered Silk Matrix based Sensing Devices for Molecular
Bioanalysis
- Aditi Sammi,
- Divya .,
- Supratim Mahapatra,
- Rahul Kumar,
- Pranjal Chandra
Supratim Mahapatra
Indian Institute of Technology BHU Varanasi
Author ProfilePranjal Chandra
Indian Institute of Technology BHU Varanasi
Author ProfileAbstract
Silk is a fibrous protein, has been a part of human lives for centuries
and was used as suture and textile material. Silk is mainly produced by
members of certain arthropods such as spiders, butterflies, mites, and
moths. However, recent biotechnological advances have revolutionized
silk as a biomaterial for various applications ranging from diverse
sensors to robust fibers. The biocompatibility, mechanical resilience,
and biodegradability of the material make it a suitable candidate for
biomaterials. Silk can also be easily converted into several
morphological forms, including fibers, films, sponges, and hydrogels.
Provided these abilities, silk has received excellent traction from
scientists worldwide for various developments, one of them being its use
as a bio-sensor. The diversity of silk materials offers various options,
giving scientists the freedom to choose from and personalize them as per
their needs. In this review, we foremost look upon the composition,
production, properties, and various morphologies of silk. The numerous
applications of silk and its derivatives for fabricating biosensors to
detect small molecules, macromolecules, and cells have been explored
comprehensively. Also, the data from various globally developed sensors
using silk have been described into organized tables for each category
of molecules, along with their important analytical details.15 Oct 2021Submitted to Biotechnology and Bioengineering 16 Oct 2021Submission Checks Completed
16 Oct 2021Assigned to Editor
28 Oct 2021Reviewer(s) Assigned
28 Nov 2021Review(s) Completed, Editorial Evaluation Pending
28 Nov 2021Editorial Decision: Revise Minor
03 Dec 20211st Revision Received
06 Dec 2021Submission Checks Completed
06 Dec 2021Assigned to Editor
08 Dec 2021Reviewer(s) Assigned
22 Dec 2021Review(s) Completed, Editorial Evaluation Pending
22 Dec 2021Editorial Decision: Accept