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A case report of an extremely rare type of cardiac tumor: Primary Cardiac Angiofibroma
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  • Aisa Talebi,
  • Sam Zeraatian Nejad Davani,
  • Ali Saberi Shahrbabaki,
  • Milad Gholizadeh Mesgarha,
  • Arash Pour Mohammad,
  • Ali Zare-Mirzaie
Aisa Talebi
Shahid Beheshti University of Medical Sciences School of Medicine
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Sam Zeraatian Nejad Davani
Iran University of Medical Sciences
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Ali Saberi Shahrbabaki
Shahid Beheshti University of Medical Sciences School of Medicine
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Milad Gholizadeh Mesgarha
Iran University of Medical Sciences

Corresponding Author:[email protected]

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Arash Pour Mohammad
Iran University of Medical Sciences
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Ali Zare-Mirzaie
Iran University of Medical Sciences
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Abstract

Cardiac angiofibroma is a very rare diagnosis when a patient develops an intracardiac mass. It is a primary benign cardiac tumor with a scarcity of information in the literature.  This case report illustrates a 26-year-old man with a complaint of chronic chest tightness who was firstly diagnosed with right ventricle tumor by echocardiography then underwent cardiac MRI which confirmed the presence of a highly-vascular tumor with radiologically benign behavior. Then his tumor was excised, his postoperative course was uncomplicated and he was well within almost 2 months after discharge. Ultimately the histopathologic findings demonstrated vascular and stromal tissue in favor of angiofibroma and excluded the other diagnoses with IHC and trichrome staining.  Angiofibroma is a benign, highly vascular tumor, mostly discovered in the nasopharynx. When it is found in the heart, CMR and pathology are pivotal to rule in its diagnosis. It is isointense in T1 weighted and hyperintense in T2 weighted sequences with intense enhancement following contrast injection. Its pathology contains an admixture of vasculatures with CD31 positive immunoreactivity for endothelial cells and fibrotic tissue with bluish coloration in trichrome staining. Eventually, its treatment includes merely surgical excision given its benign nature.
20 Nov 2021Submitted to Journal of Cardiac Surgery
20 Nov 2021Submission Checks Completed
20 Nov 2021Assigned to Editor
22 Nov 2021Reviewer(s) Assigned
01 Dec 2021Review(s) Completed, Editorial Evaluation Pending
01 Dec 2021Editorial Decision: Revise Minor
07 Dec 20211st Revision Received
07 Dec 2021Submission Checks Completed
07 Dec 2021Assigned to Editor
07 Dec 2021Reviewer(s) Assigned
13 Dec 2021Review(s) Completed, Editorial Evaluation Pending
13 Dec 2021Editorial Decision: Accept
Mar 2022Published in Journal of Cardiac Surgery volume 37 issue 3 on pages 688-692. 10.1111/jocs.16187