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Extrarenal Wilms tumor with hypertension and dilated cardiomyopathy in an infant: A case report and review of the literature
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  • yanning Qu,
  • Yurui Wu,
  • Dong Qu,
  • Haiyan Ge
yanning Qu
Capital Institute of Pediatrics

Corresponding Author:[email protected]

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Yurui Wu
Capital Institute of Pediatrics
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Dong Qu
Capital Institute of Pediatrics
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Haiyan Ge
Capital Institute of Pediatrics
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Abstract

While Wilms tumors are the most frequently detected renal cancer type in children, extrarenal Wilms tumors (ERWTs) remain rare. This report is the first to describe hypertension and dilated cardiomyopathy in a patient with an ERWT. A six-month-old male infant presented with an abdominal mass and paroxysmal hypertension, echocardiography revealed dilated cardiomyopathy with an ejection fraction of 34%, as well as substantially increased plasma renin activity. Pathology yielded a definitive diagnosis of ERWT. Cardiac function and blood pressure gradually returned to normal after tumorectomy. The early diagnosis of such a tumor together with efficient oncologic treatment are vital to optimal patient outcomes.
16 May 2022Submitted to Pediatric Blood & Cancer
16 May 2022Submission Checks Completed
16 May 2022Assigned to Editor
17 May 2022Reviewer(s) Assigned
29 May 2022Review(s) Completed, Editorial Evaluation Pending
31 May 2022Editorial Decision: Revise Minor
08 Jun 2022Submission Checks Completed
08 Jun 2022Assigned to Editor
08 Jun 20221st Revision Received
09 Jun 2022Reviewer(s) Assigned
23 Jun 2022Review(s) Completed, Editorial Evaluation Pending
27 Jun 2022Editorial Decision: Revise Minor
28 Jun 20222nd Revision Received
28 Jun 2022Submission Checks Completed
28 Jun 2022Assigned to Editor
29 Jun 2022Reviewer(s) Assigned
05 Jul 2022Review(s) Completed, Editorial Evaluation Pending
06 Jul 2022Editorial Decision: Accept