Successful treatment with bortezomib for POEMS syndrome, overcoming
complicated severe heart block
- Yuichi Nakamura
, - Yoshihiro Itoh,
- Naoki Wakimoto,
- Ryu Kanno,
- Shinichirou Iida,
- Keiji Yamamoto
Abstract
Cardiac bradyarrhythmia and conduction disorder may be rare, but
recurrent adverse events caused by bortezomib. Here we report a case
with POEMS syndrome presenting severe heart block after bortezomib plus
dexamethasone therapy. After permanent pacemaker implantation,
bortezomib was restarted and maintained, resulting in sustained complete
response for POEMS syndrome.14 Nov 2022Submitted to Clinical Case Reports 14 Nov 2022Submission Checks Completed
14 Nov 2022Assigned to Editor
10 Dec 2022Reviewer(s) Assigned
23 Dec 2022Review(s) Completed, Editorial Evaluation Pending
06 Jan 2023Editorial Decision: Revise Minor
08 Jan 20231st Revision Received
11 Jan 2023Submission Checks Completed
11 Jan 2023Assigned to Editor
11 Jan 2023Review(s) Completed, Editorial Evaluation Pending
06 Feb 2023Editorial Decision: Accept
