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Tranexamic acid soaked NasoPore® to improve the management of epistaxis
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  • Eleanor Rosario,
  • Ekta Sharma,
  • Ankit Patel,
  • Gabrielle Guvensen,
  • Rizal Ashroff,
  • Fiona McClenaghan,
  • Ahmad Hariri,
  • Jonathan Joseph
Eleanor Rosario
University College London Hospitals NHS Foundation Trust

Corresponding Author:[email protected]

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Ekta Sharma
University College London Hospitals NHS Foundation Trust
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Ankit Patel
University College London Hospitals NHS Foundation Trust
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Gabrielle Guvensen
University College London Medical School
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Rizal Ashroff
University College London Hospitals NHS Foundation Trust
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Fiona McClenaghan
University College London Hospitals NHS Foundation Trust
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Ahmad Hariri
St. Mary's Hospital
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Jonathan Joseph
University College London Hospitals NHS Foundation Trust
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Abstract

Objectives The aim of this study was to assess the efficacy of a new emergency department intervention for the management of epistaxis, aiming to reduce epistaxis admissions. Design Tranexamic acid (TXA) (500mg/ml) soaked NasoPore® packing was in the pathway for epistaxis which did not terminate following 10 minutes of simple first aid. The pathway was utilised for adult patients presenting with non-traumatic, anterior epistaxis. Pre- and post-implementation admission rates and re-attendance rates were recorded by retrospective audit at a large central London hospital. Results Epistaxis admissions were reduced by 51.7% (p<0.05) following the implementation of the TXA-soaked NasoPore® pathway. Conclusions The significant reduction in epistaxis admissions demonstrates that this intervention is beneficial for patient outcomes. This has the potential to be introduced in other A&E departments and also pre-hospital settings.
13 Nov 2022Submitted to Clinical Otolaryngology
16 Nov 2022Submission Checks Completed
16 Nov 2022Assigned to Editor
27 Nov 2022Reviewer(s) Assigned
06 Jan 2023Review(s) Completed, Editorial Evaluation Pending
12 Feb 2023Editorial Decision: Revise Major
12 May 20231st Revision Received
19 May 2023Submission Checks Completed
19 May 2023Assigned to Editor
20 May 2023Reviewer(s) Assigned
08 Jul 2023Review(s) Completed, Editorial Evaluation Pending
15 Jul 2023Editorial Decision: Revise Minor
18 Jul 20232nd Revision Received
26 Jul 2023Submission Checks Completed
26 Jul 2023Assigned to Editor
30 Jul 2023Reviewer(s) Assigned
01 Aug 2023Review(s) Completed, Editorial Evaluation Pending
03 Aug 2023Editorial Decision: Accept