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Hyper IgE Syndrome Related Disease Treated with Dupilumab: A Case Report
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  • Andrew Kao,
  • Hany Deirawan,
  • Pavadee Poowuttikul,
  • Steven Daveluy
Andrew Kao
Wayne State University School of Medicine

Corresponding Author:[email protected]

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Hany Deirawan
Wayne State University School of Medicine
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Pavadee Poowuttikul
Central Michigan University College of Medicine
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Steven Daveluy
Wayne State University School of Medicine
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Abstract

We describe a case of a 2-month-old female displaying clinical phenotype of HIES related disease with severe eczematous dermatitis recalcitrant to corticosteroids. Genetic panel showed a variant of unknown significance in key immune regulator of PGM3. Patient achieved nearly complete response from off-label use of dupilumab.

Peer review status:ACCEPTED

13 Feb 2023Submitted to Clinical Case Reports
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15 Feb 2023Submission Checks Completed
15 Feb 2023Assigned to Editor
17 Feb 2023Reviewer(s) Assigned
15 Apr 2023Review(s) Completed, Editorial Evaluation Pending
26 Apr 2023Editorial Decision: Revise Minor
07 May 20231st Revision Received
09 May 2023Submission Checks Completed
09 May 2023Assigned to Editor
09 May 2023Review(s) Completed, Editorial Evaluation Pending
25 May 2023Editorial Decision: Accept