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Loss Of Humeral Immunity In Childhood Cancer Survivors Not Having Undergone Hematopoietic Stem Cell Transplantation.
  • +2
  • Nicole Baca,
  • Benjamin Pearson,
  • Michelle Pulley,
  • Marcio Diniz,
  • Fataneh Majlessipour
Nicole Baca
Cedars-Sinai Medical Center

Corresponding Author:[email protected]

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Benjamin Pearson
University of Richmond
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Michelle Pulley
Cedars-Sinai Medical Center
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Marcio Diniz
Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute
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Fataneh Majlessipour
Cedars-Sinai Medical Center
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Abstract

There is limited and conflicting data regarding loss of immunity in childhood cancer survivors who did not undergo hematopoietic stem cell transplantation. This retrospective study included 28 childhood cancer survivors whose treatment consisted of at least 3 months of chemotherapy. Decreased seropositivity for measles, mumps, rubella, varicella, tetanus, and hepatitis B was found in patients across all categories of malignancy compared to the general population. Results were more pronounced for those with hematological malignancies. This study indicates that pediatric cancer survivors, especially those with hematological malignancies, may have greater loss of protective antibodies from primary vaccinations.
30 Mar 2023Submitted to Cancer Reports
01 Apr 2023Review(s) Completed, Editorial Evaluation Pending
01 Apr 2023Submission Checks Completed
01 Apr 2023Assigned to Editor
06 Apr 2023Reviewer(s) Assigned
04 May 2023Editorial Decision: Revise Major
01 Jun 20231st Revision Received
15 Jun 2023Submission Checks Completed
15 Jun 2023Assigned to Editor
15 Jun 2023Review(s) Completed, Editorial Evaluation Pending
21 Jun 2023Reviewer(s) Assigned
17 Jul 2023Editorial Decision: Revise Minor
29 Jul 20232nd Revision Received
07 Aug 2023Submission Checks Completed
07 Aug 2023Assigned to Editor
07 Aug 2023Review(s) Completed, Editorial Evaluation Pending
11 Aug 2023Reviewer(s) Assigned
14 Sep 2023Editorial Decision: Accept