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Synthesis of C2,3-vicinal diaminoindoles via a copper-iodine co-catalytic strategy
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  • Wenhua Yu,
  • Yingying Zhang,
  • Xiaoxiang Zhang,
  • Xiaoting Gu,
  • Xirui Qing,
  • Wanxing Wei,
  • Zhuan Zhang,
  • Guanghua Li,
  • Taoyuan Liang
Wenhua Yu
Guangxi University
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Yingying Zhang
Guangxi University
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Xiaoxiang Zhang
Guangxi University
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Xiaoting Gu
Guangxi University
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Xirui Qing
Guangxi University
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Wanxing Wei
Guangxi University
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Zhuan Zhang
Guangxi University
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Guanghua Li
Guangxi University
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Taoyuan Liang
Guangxi University

Corresponding Author:[email protected]

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Abstract

A one-pot synthesis of vicinal diamines using indoles, pyrazoles, and phenothiazines in a tandem multi-component reaction is developed. The utilization of a copper-iodine co-catalytic system enables the generation of a diverse range of vicinal diaminoindoles with good selectivity and moderate to good yields. An attractive aspect of this method is that it can be conducted under mild and environmentally friendly conditions, showcasing its potential as an alternative approach for synthesizing vicinal diamines. Moreover, the use of a multicomponent tandem reaction highlights the power and versatility of such strategies in synthetic chemistry.
17 Aug 20231st Revision Received
18 Aug 2023Submission Checks Completed
18 Aug 2023Assigned to Editor
18 Aug 2023Review(s) Completed, Editorial Evaluation Pending
23 Aug 2023Editorial Decision: Accept