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Electrochemical dearomative spirocyclization of N-acyl sulfona-mides in a continuous-flow cell
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  • Ting Liu,
  • Zhaojiang Shi,
  • Yaofeng Yuan,
  • Yuqi Lin,
  • Keyin Ye
Ting Liu
Fuzhou University
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Zhaojiang Shi
Fuzhou University
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Yaofeng Yuan
Fuzhou University
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Yuqi Lin
Fuzhou University
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Keyin Ye
Fuzhou University

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Abstract

The development of efficient and sustainable methods to obtain spirocyclic compounds is of significance as these structures are widely found in pharmaceuticals and agrochemicals. Herein, we disclose an electrochemical dearomative spirocyclization of N-acyl sulfonamides in a continuous-flow cell. The reaction is simple and efficient without external catalysts or supporting electrolytes, in-cluding a decagram-scale synthesis.
09 Nov 2023Submitted to Chinese Journal of Chemistry
13 Nov 2023Submission Checks Completed
13 Nov 2023Assigned to Editor
13 Nov 2023Review(s) Completed, Editorial Evaluation Pending
15 Nov 2023Reviewer(s) Assigned