The Relationship Between COVID-19 Suspected Patient's Coagulation and
Platelet Parameters and Polimerase Chain Reaction Results
Abstract
Aim: Our aim was to investigate the relationship between
prothrombintime(PT), activated partial thromboplastin time (aPTT), INR
(International Normalized Ratio) and D-dimer levels, platelet
(PLT)levels at admission to hospital and positivity or negativity of
Polymerase Chain Reaction (PCR) result in patients with suspected
COVID-19 followed at COVID-19 services. Material and Method: 238 people
who applied with suspicion of COVID-19 in March-April-May of 2020 were
included in the study. According to COVID-19 results, PCR negative 119
participants and PCR positive 119 patients were included in the study.
PT, aPTT, Ddimer, INR and PLT levels were examined. Results: While PCR
negative participants had a mean PT value of 11.46±0.86 sec, PCR
positive patients had a mean PT value of 12.97±3.65 sec
(p<0.001). There was no significant difference in mean aPTT
values of PCR positive and negative patients. Whereas INR, D-dimer
increased significantly in PCR positive patients. PLT value decreased
from mean value of 266.75±71.36*109/L in PCR negative participants to
241.18±96.64*109/L in PCR positive patients (p=0.002). Conclusion: In
our study, it was found that in patients who were admitted to Samsun
Training and Research Hospital with COVID-19 suspicion and followed up
in COVID-19 services, PT, D-dimer, INR, PLT values were important in
detecting Coagulopathy and Thrombocytopenia in the group who were PCR
positive according to COVID-19 results. Keywords: COVID-19, PT, aPTT,
D-dimer, INR, PLT