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Effect of hemodialysis on left atrial function in patients with end-stage renal failure evaluated by two-dimensional speckle tracking Imaging
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  • Yunxiang Miao,
  • Li Wang,
  • Ying Yin,
  • BingYuan Zhou,
  • Yuping Liao
Yunxiang Miao
First Affiliated Hospital of Soochow University
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Li Wang
First Affiliated Hospital of Soochow University
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Ying Yin
First Affiliated Hospital of Soochow University
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BingYuan Zhou
First Affiliated Hospital of Soochow University
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Yuping Liao
First Affiliated Hospital of Soochow University

Corresponding Author:[email protected]

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Abstract

Abstract Objective: We sought to evaluate the left atrial (LA) strain parameters of maintenance hemodialysis (MHD) patients before and after dialysis by two dimensional speckle tracking imaging (2D- STI), and to explore the effect of volume load change on LA function. Methods: 76 patients with end stage renal disease (ESRD) on hemodialysis (HD) were enrolled in the study protocol. The median duration of dialysis was 24.0 (7.5, 59.5) months. In addition, 30 healthy subjects were selected as control group. Comprehensive echocardiography was performed immediately before and after hemodialysis to compare the changes in left atrial function. Results: Regarding LA strain parameters in patients of pre-HD, the median (25th, 75th) LA reservoir, LA conduit, and LA contractile reserve were 28.0 (23.0, 34.5), -15.5 (-10.0, -21.5),-12.0 (-9.0, -16.0) respectively; the post-HD were 26.0 (21.0, 29.0), -12.0 (-9, -15.5), -12.5 (-9, -15.5) respectively; and controls were 43.0 (36.0, 48.0), -24.0 (-18.0, -32.0), -17.0 (-15.0, -22.0) respectively. The left atrial strain parameters before HD were lower than controls, the differences were statistically significant (P < 0.05). The reservoir function and conduit function of LA strain decreased after hemodialysis, the differences were statistically significant (P < 0.05). Regarding the contraction of LA, the differences between pre- and post-HD were not statistically significant (p > 0.05). Conclusion: New echocardiographic parameters, such as left atrial strain, can quantitatively evaluate the changes in left atrial function before and after hemodialysis in ESRD patients, which can provide valuable information for the overall cardiac evaluation in this specific population.
Submitted to Echocardiography
25 Jan 20241st Revision Received
29 Jan 2024Assigned to Editor
29 Jan 2024Submission Checks Completed
29 Jan 2024Review(s) Completed, Editorial Evaluation Pending
29 Jan 2024Reviewer(s) Assigned
03 Feb 2024Editorial Decision: Revise Minor
04 Feb 20242nd Revision Received
05 Feb 2024Submission Checks Completed
05 Feb 2024Assigned to Editor
05 Feb 2024Review(s) Completed, Editorial Evaluation Pending
05 Feb 2024Editorial Decision: Accept